Acute Treatment
Clot busters, e.g., tPA
The most promising treatment for ischemic stroke is the FDA-approved clot-busting drug tPA (tissue plasminogen activator), which must be administered within a three-hour window from the onset of symptoms to work best. Administering tPA or other clot-dissolving agents is complex and is done through an intravenous (IV) line in the arm by hospital personnel. If given promptly, tPA can significantly reduce the effects of stroke and reduce permanent disability. Generally, only 3 to 5 percent of those who suffer a stroke reach the hospital in time to be considered for this treatment.
Clot busters, e.g., tPA
The most promising treatment for ischemic stroke is the FDA-approved clot-busting drug tPA (tissue plasminogen activator), which must be administered within a three-hour window from the onset of symptoms to work best. Administering tPA or other clot-dissolving agents is complex and is done through an intravenous (IV) line in the arm by hospital personnel. If given promptly, tPA can significantly reduce the effects of stroke and reduce permanent disability. Generally, only 3 to 5 percent of those who suffer a stroke reach the hospital in time to be considered for this treatment.
Preventive Treatment
Anticoagulants/Antiplatelets
Antiplatelet agents such as aspirin and anticoagulants such as warfarin interfere with the blood's ability to clot and can play an important role in preventing stroke. Read more about anticoagulants.
Carotid Endarterectomy 
Carotid endarterectomy, also called carotid artery surgery, is a procedure in which blood vessel blockage (fataty plaque) is surgically removed from the carotid artery. View a detailed illustration of carotid endarterectomy.
Angioplasty/Stents
Doctors sometimes use balloon angioplasty and implantable steel screens called stents to treat cardiovascular disease and reduce fatty buildup clogging a vessel.
Hemorrhagic Stroke (Subarachnoid hemorrhage or AVM)
Surgical Intervention
For hemorrhagic stroke (specifically for a subarachnoid hemorrhage), surgical treatment is often recommended to either place a metal clip at the base, called the neck, of the aneurysm or to remove the abnormal vessels comprising an arteriovenous malformation (AVM). Learn more about AVM.
Endovascular Procedures, e.g., "coils"
Endovascular procedures are less invasive and involve the use of a catheter introduced through a major artery in the leg or arm, guided to the aneurysm or AVM where it deposits a mechanical agent, such as a coil, to prevent rupture. Learn more about aneurysms.
Clinical Trials
Clinical trials are scientific studies that determine if a possible new medical advance can help people and whether it has harmful side effects. Find answers to common questions about clinical trials in our Guide to Understanding Clinical Trials.
This content was last reviewed on 10/23/2012.

Have you or someone you love had a stroke? There is a life after stroke, and we're here to help. Find support and resources to help you make the most of your recovery.



