AHA/ASA Cryptogenic Stroke Initiative_1454687095446

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Stroke Survivor Story: Overcoming the Unknown

understanding diagnosis and treatment of cryptogenic stroke: healthcare professional toolkit   understanding cryptogenic stroke:  a patient guide

about the cryptogenic initiative


Each year, about one third of ischemic strokes in the United States — about 200,000 — are classified as cryptogenic (no definitive cause). The American Heart Association/American Stroke Association’s Cryptogenic Stroke Initiative, sponsored by Medtronic, is elevating the issue of cryptogenic stroke.

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Complexity in diagnosing and treating cryptogenic stroke potential causes

With limited guidelines, many professionals diagnose and treat cryptogenic stroke differently. Understanding the complex issues in treating cryptogenic patients can reduce stroke recurrence and improve outcomes.


Atrial fibrillation (afib or AF) is one of the potential causes of cryptogenic stroke — increasing risk five times. AF can go undetected because it often has no symptoms and may occur infrequently. Other causes for cryptogenic stroke include Patent Foreman Ovale (PFO), inherited thrombophilias, aortic arch plaque, infectious, autoimmune and inflammatory states.

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medtronic supports the cryptogenic stroke initiative